Best CBB Betting Odds Of The Day: Louisville Underdogs vs. Duke

  • The Duke Blue Devils have -145 short odds to beat the Louisville Cardinals.
  • The Iowa State Cyclones are the +475 underdog to take out the No. 25 Oklahoma Sooners.
  • The Butler Bulldogs have +215 longshot odds to beat the Xavier Musketeers.

LOUISVILLE, Ky. – Sports betting fans are placing major action on college basketball games with March Madness just around the corner.

The big matchups that are garnering a lot of attention at online sportsbooks are Duke Blue Devils vs. Louisville Cardinals, Oklahoma Sooners vs. Iowa State Cyclones, and Xavier Musketeers vs. Butler Bulldogs.

There are many betting lines surrounding these big games, giving college basketball betting fans plenty of action to wager on.

Duke Blue Devils vs. Louisville Cardinals Odds

  • Moneyline: Duke -155, Louisville +135
  • Spread: Duke -2.5
  • Totals: Over/Under 140

Duke has had an up and down season so far this year, currently sitting near the bottom of the conference headed into the tournament.

Sports betting fans are still pulling for the Blue Devils, making them the favorite despite having the lower seed and worse record compared to Louisville.

What Blue Devils fans may be hoping for is the potential play of Mathew Hurt who leads the team in points (18.2 PPG) and rebounds (6.3 RPG). A good game from the sophomore forward could lead to major wins at online sportsbooks.

Smart money is on Louisville, however. The Cardinals have been better all season, ranked higher in the ACC, and have the  multiple players averaging double figures on the season.

Taking the +135 long odds on the should be favored Cardinals should be a no-brainer. But, it is March after all and madness is everywhere in college basketball.

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Iowa State Cyclones Vs. Oklahoma Sooners Odds

  • Moneyline: Oklahoma -750, Iowa State +475
  • Spread: Oklahoma -11.5
  • Totals: Over/Under 142

This betting line is a lot more one-sided, as the Cyclones have been awful all season both defensively and offensively, sitting at the bottom of the Big 12 conference, and have not one a single conference game this year.

Sports betting fans looking to wager on this game and don’t believe in a miracle upset for Iowa State may want to place action on an alternate spread for Oklahoma.

Taking the Sooners at -15.5 would net sports betting fans a +150 return on their wager. Iowa State has lost to Oklahoma state 58-76 earlier in the season, and more recently last to Texas Tech 54-81.

It is possible for Oklahoma to cover the -15.5 spread and have sports betting fans cashing in big.

Butler Bulldogs vs. Xavier Musketeers Odds

  • Moneyline: Xavier -260, Butler +215
  • Spread: Xavier -6.0
  • Totals: Over/Under 133.0

Sports betting fans are leaning heavily on the Musketeers, as they had a better season are higher in the Big East standings than Butler, but not by much.

Both Butler and Xavier are middling teams, and the game could go either way; a good thing for longshot betting fans.

Xavier won the last matchup with Butler 78-63, with a standout performance from senior guard Paul Scruggs.

Scruggs on the season is a solid player, but his 24-3-7 game against the Bulldogs earlier in the season was an aberration, and likely won't happen in the next matchup.

Longshot betting fans should lean in on the +215 long odds for Butler to pull the upset, as the Bulldogs could come out with the win in this matchup.