Breaking Down The Top 25 Matchups In Week 12 Of College Football

  • Ohio State has -1100 odds to beat Indiana.
  • Wisconsin is favored to take down Northwestern with -300 odds.
  • Oklahoma has -260 odds to defeat Oklahoma State.

COLUMBUS, Ohio.College football bettors have plenty of games to look forward to in Week 12 of the season as there are a total of 15 games that include a top-25 ranked team. Of those 15 games, three of them include matchups within the top-25.

Online sportsbooks have odds on all of the top-25 games for Week 12 which includes a matchup between #3 Ohio State and #9 Indiana, #10 Wisconsin and #19 Northwestern, and also #14 Oklahoma State and #18 Oklahoma.

Top 25 Matchups

  • #3 Ohio State (-1100) vs. #9 Indiana (+650)
  • #4 Clemson (-35.5) vs. Florida State
  • #6 Florida (-31.5) vs. Vanderbilt
  • #15 Coastal Carolina (-200) vs. Appalachian State (+170)
  • #8 BYU (-48) vs. North Alabama
  • #7 Cincinnati (-220) vs. UCF (+180)
  • #10 Wisconsin (-300) vs. #19 Northwestern (+250)
  • #11 Oregon (-900) vs. UCLA (+550)
  • #1 Alabama (-30.0) vs. Kentucky
  • #17 Iowa State (-420) vs. Kansas State (+310)
  • #23 Auburn (-420) vs. Tennessee (+310)
  • #13 Georgia (-2500) vs. Mississippi State (+1050)
  • #14 Oklahoma State (+215) vs. #18 Oklahoma (-260)
  • #21 Liberty (+145) vs. NC State (-165)
  • #20 USC (-140) vs. Utah (+120)

#3 Ohio State Vs. #9 Indiana, 12:00 p.m. EST

  • Ohio State (-1100) vs. Indiana (+650)
  • Spread: Ohio State -20.5
  • Total: 67 Points

Ohio State and Indiana will be facing off for their 93rd all-time meeting in history in Week 12 of the college football season. Ohio State holds a huge advantage over Indiana as they have won 75 of those games to Indiana’s 12. There have also been five ties in the series as well.

Also, Ohio State currently is on a 24-game win streak against the Hoosiers that dates back to 1991 which is certainly why their college football odds are heavily favored.

In Ohio States' last eight games as a home favorite, they have gone 6-2 against the spread.

In the last 12 games that Indiana has come off of a bye week, the Over for the point total has gone 10-2.

In the last nine meetings between the two, the underdog - which has been the Hoosiers in all nine - have gone 7-2 against the spread.

#10 Wisconsin vs. #19 Northwestern, 3:30 p.m.

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  • Wisconsin (-300) vs. Northwestern (+250)
  • Spread: Wisconsin -7.5
  • Total: 59 Points

The Wisconsin Badgers and Northwestern Wildcats have seen each other a total of 101 times and in Week 12 of the NCAA season, they will meet once more.

Wisconsin holds a hefty lead in the series as they have won 60 games to Northwestern’s 36 while there have also been five ties.

As for ongoing trends in the matchup, in Wisconsin’s last seven games as the favorite, the Over for the point total has gone 7-0.

In Northwestern’s last five games overall, they have gone 4-0-1 against the spread. Also, in their last six meetings, the underdog going into the game has gone 5-1 against the spread.

#14 Oklahoma State vs. #18 Oklahoma

  • Oklahoma State (+215) vs. Oklahoma (-260)
  • Spread: Oklahoma -7
  • Total: 59 Points

The Oklahoma Sooners will be taking on their in-state rivals, the Oklahoma State Cowboys in Week 12. The Sooners hold a large advantage thus far in their 114 meetings as they have won 89 games to Oklahoma State’s 18 (7 ties).

The Sooners have also won the last five meetings between the two as well.

An edge may be that in Oklahoma State’s last five games as a road underdog, they have gone 5-0 against the spread. Also, the Sooners' last six games as the favorite have resulted in the over hitting five times.

But perhaps the most telling is the road advantage. In the last eight meetings, the road team has gone 7-1 against the spread.