NFL Betting Preview: Kansas City Chiefs Vs. Cleveland Browns

  • The Kansas City Chiefs are -245 favorites to beat the Cleveland Browns +205 in Week 1 of the 2021-2022 NFL season.
  • WR Odell Beckham Jr. is questionable to play for the Browns on Sunday.
  • The spread for this matchup is set at -5.5 Chiefs.

KANSAS CITY, Mo. – Week 1 of the NFL season is here and big matchups are available for betting fans to cash in on. The Kansas City Chiefs are hosting the Cleveland Browns on Sunday, September 12, with a number of sports bettors wagering on this matchup.

This is the most gambled on game of Week 1 according to sportsbooks and odds show betting fans are leaning heavily in favor of Kansas City to win their first game of the season.

Cleveland Browns Vs. Kansas City Chiefs

  • Chiefs Moneyline -245
  • Browns Moneyline +205
  • Spread Chiefs -5.5
  • Total O/U 54.5

Sportsbooks are keeping the game close, however, with the spread set at just -5.5 which may be a sign for underdog betting fans to jump on these odds with NFL sportsbooks.

Benefits For Underdogs

This Cleveland Browns team is not the same group that lost 17-22 against Kansas City in the AFC Division playoffs game. While the Browns’ stellar defense and the strong running game are still intact, Odell Beckham Jr. may also be making his return.

Right now, Odell is still listed as questionable, but if he is able to play it could be the difference-maker. The Kansas City Chiefs defense was top 10 in both rushing and passing defense, but also have a habit of giving up points when the Chiefs are up early.

If Odell plays and gives a spark to the Browns’ offense, this could lead to a game that forces Kansas City to work for all four quarters which works in the Browns’ favor.

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Sportsbooks have the Chiefs winning by under a touchdown, so even bookmakers do not see the Chiefs as big favorites despite the odds.

Longshot betting fans could also play it safe and take the Browns to cover +5.5, which would net returns even if Cleveland loses but manages to keep it close.

Alternate Spreads

Outside of taking the main moneyline and spread, sports betting fans could see bigger returns taking alternate spreads. USA online sportsbooks have the Chiefs spread at -7.5 with+130 odds.

For sports bettors who are confident in Kansas City, they can take the Chiefs to cover the bigger spread and win big if the team manages to win by more than sportsbooks expect them to.

Player Props

Spreads are not the only betting options available either. Fans can see big wins betting on player props like total passing yards for each QB.

Baker Mayfield (CLE) Passing Yards

  • OVER (260.5) -114
  • UNDER (260.5) -114

Both these totals are set higher than each player’s averages last season. Patrick Mahomes averaged 309.5 yards per game during the 2020 NFL season and Baker Mayfield averaged  222.7.

Patrick Mahomes (KC) Passing Yards

  • OVER (312.5) -114
  • UNDER (312.5) -114

The Chiefs defense’s habit of giving up points in the second half, and the potential of Odell Beckham Jr. playing could see Baker Mayfield hitting the OVER in this game. On the other side of things, Patrick Mahomes hitting the OVER on any given Sunday is always a potential threat.

These player props and other betting lines are all live right now for NFL bettors to wager on. The game kicks off on Sunday at 4:25 PM ET on CBS.