NFL Week 1 Betting Odds For Primetime Games Favor Home Teams

  • The Kansas City Chiefs host the Baltimore Ravens on Thursday Night Football as 2.5-point favorites as the first game of the 2024-2025 NFL season.
  • Week 1 betting odds favor the Philadelphia Eagles by 2.0 points against the Green Bay Packers in Sao Paulo, Brazil on Friday, September 6.
  • Sunday Night football features a playoffs rematch between the Los Angeles Rams and Detroit Lions (-3.5) and the San Francisco 49ers (-6.0) face the New York Jets on Monday Night Football.

KANSAS CITY, Mo. – Week 1 betting odds are available after the NFL officially released the 2024-2025 NFL season schedule on Wednesday night. The Kansas City Chiefs are 2.5-point favorites at online sportsbooks in the first game of the season.

Baltimore Ravens Vs Kansas City Chiefs Betting Odds

Team Spread Moneyline Total
Baltimore Ravens +2.5 (EVEN) +125 O46.5 (-110)
Kansas City Chiefs -2.5 (-120) -145 U46.5 (-110)

Thursday Night Football features an AFC Championship rematch between the Ravens and Chiefs. After beating the Ravens by seven points on the road last season, Missouri online sportsbooks favor Kansas City with -145 odds.

Green Bay Packers Vs Philadelphia Eagles Betting Odds

Team Spread Moneyline Total
Green Bay Packers +2.0 (-105) +115 O48.5 (-115)
Philadelphia Eagles -2.0 (-115) -135 U48.5 (-105)

The NFL announced that two of the most accomplished NFL franchises will meet in the first-ever NFL game in South America. The Philadelphia Eagles are 2.0-point favorites as the “home” team over the youthful Green Bay Packers for a Friday night-edition of NFL football.

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Week 1 Betting Odds For Sunday Night and Monday Night Football

LA Rams Vs Detroit Lions Betting Odds

Team Spread Moneyline Total
Los Angeles Rams +3.5 (-115) +140 O51.5 (-110)
Detroit Lions -3.5 (-105) -165 U51.5 (-110)

The Lions took down the Rams 24-23 in an exciting NFC wild-card round meeting last season. They’ll meet again on Sunday Night Football, where NFL online sportsbooks favor the Lions by 3.5 points in Detroit.

New York Jets Vs San Francisco 49ers Betting Odds

Team Spread Moneyline Total
New York Jets +6.0 (-115) +210 O45.5 (-110)
San Francisco 49ers -6.0 (-105) -250 U45.5 (-110)

New York Jets head coach Robert Saleh faces his former team as 6.0-point underdogs. A showdown between two of the league’s best defenses leans the 45.5-point total at California online sportsbooks to go under on Monday Night Football.