Nick Kyrgios vs. Karen Khachanov Betting Odds Breakdown

  • Nick Kyrgios was a +150 underdog to Daniil Medvedev and defeated him.
  • Now, he’s a +165 favorite to win the entire US Open.
  • He faces Karen Khananov on Tuesday, with -425 odds to win.

NEW YORK – Nick Kyrgios defeated Daniil Medvedev, the number one player in the world, for the second time in the last few months at the US Open, and moved into a dominant position atop the odds to win the US Open.

Kyrgios entered his matchup against Medvedev as a +150 underdog, but defeated Medvedev in four sets.

Now, he sits alone as the favorite to win the US Open, as the only player with odds under +200 to do so.

Men’s US Open Odds 2022

  • Nick Kyrgios +165
  • Carlos Alcaraz +225
  • Jannik Sinner +500
  • Matteo Berrettini +1100
  • Casper Ruud +1200
  • Frances Tiafoe +1200
  • Andrey Rublev +1400
  • Karen Khachanov +2500

At the very bottom of those odds boards – no double due to the fact that he faces Kyrgios – is Karen Khachanov, Kyrgios’ next opponent.

US Open 2022 – Nick Kyrgios vs. Karen Khachanov Odds

  • Nick Kyrgios -425
  • Karen Khachanov +325

If the sportsbooks were less-than-sold on Kyrgios four days ago, they’re surely sold on him now, favoring him over the former world No. 8 by a huge margin.

The two haven’t faced off since 2020, so this matchup is a relatively novel one given Kyrgios’ recent run of form.

In 2020, Kyrgios took the victory in five sets, while in their previous matchup in 2019, Khachanov won a three-set match with a 2-1 score.

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This is Khachanov’s first time in the quarterfinals of the US Open, although his victory over Pablo Carreno Busta says that perhaps he’s here to play, rather than to be Kyrgios’ latest victim.

It’s worth noting that both of the matchups these two have had have taken the maximum number of sets to be resolved.

US Open 2022 – Nick Kyrgios vs. Karen Khachanov Total Sets Odds

  • Over 3.5 -165
  • Under 3.5 +125

However, Kyrgios’ recent dominance does cast some doubt on whether or not one can trust statistics from before his recent run of good form.

Still, the fact that the odds for total sets is set at 3.5 means that the online sportsbooks expect there’s a decent chance Kyrgios takes it in straight sets – something he’s never done against Khachanov.

Karen Khachanov and Nick Kyrgios face off in the US Open Quarterfinals at 8:15 p.m. EDT.