Betting 49ers to Cover 7.5-Point Spread, McCaffrey to Score

  • The San Francisco 49ers are 7.5-point favorites against the Seattle Seahawks on Thanksgiving.
  • Christian McCaffrey has -200 odds to score an anytime touchdown against Seattle.
  • The under is 11-5 in the last 16 Thanksgiving night games.

SEATTLE – The Seattle Seahawks are 7.5-point home underdogs to the San Francisco 49ers in the evening Thanksgiving game. Seattle is 1-6 against the spread in their last seven games as a home underdog.

Betting odds at USA online sportsbooks favor the 49ers to cover the 7.5-point spread with -115 odds. San Francisco covered the spread in all three matchups with Seattle last season, including two spreads greater than 8.0 points.

San Francisco 49ers Vs Seattle Seahawks Betting Odds

Team Spread Moneyline Total
San Francisco 49ers -7.5 (-115) -340 O 44.0 (-110)
Seattle Seahawks +7.5 (-105) +270 U 44.0 (-110)

Since their three-game losing skid, the 49ers outscored the Jacksonville Jaguars and Tampa Bay Buccaneers 61-17. San Francisco’s team total has -130 odds to go over 24.5 points.

The Seahawks allow 21.8 points per game while the 49ers allow the NFL-fewest 15.7 points per game. Seattle’s team total at 19.5 points has -150 odds at Washington online sportsbooks to go under on Thanksgiving.

Betting odds and team totals favor a lopsided 49ers victory that goes under the total. This aligns with Thanksgiving betting trends that show 11 of the last 16 evening Thanksgiving games went under the total.

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The 44.0-point total at NFL online sportsbooks has -110 odds to go under. San Francisco totals went under in three of their last four games and Seattle totals went under in five of their last seven.

Anytime Touchdown Odds

Chrisitan McCaffrey leads the anytime touchdown scorer odds board with -200 odds to find pay dirt Thursday. McCaffrey scored a touchdown in 18 of his last 19 games.

Anytime Touchdown Scorer Odds

  • Christian McCaffrey -200
  • Kenneth Walker III +137
  • Zach Charbonnet +140
  • Brandon Aiyuk +150
  • Deebo Samuel +150
  • George Kittle +162
  • D.K Metcalf +240
  • Tyler Lockett +240
  • DeeJay Dallas +300
  • Jauan Jennings +375
  • Jaxon Smith-Njigba +375
  • Brock Purdy +550

Brandon Aiyuk has good value at California online sportsbooks with +150 odds. Aiyuk scored a touchdown in back-to-back games and has  four touchdowns on the season.